Loading...
The cytosolic tail of the tumor marker protein Trop2 - a structural switch triggered by phosphorylation
Trop2 is a transmembrane signaling glycoprotein upregulated in stem and carcinoma cells. Proliferation-enhancing signaling involves regulated intramembrane proteolytic release of a short cytoplasmic fragment, which is later engaged in a cytosolic signaling complex. We propose that Trop2 function is...
Na minha lista:
| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2015
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4434849/ https://ncbi.nlm.nih.gov/pubmed/25981199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10324 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|