Integrated Genomics Identifies Convergence of Ankylosing Spondylitis with Global Immune Mediated Disease Pathways

Ankylosing spondylitis(AS), a highly heritable complex inflammatory arthritis. Although, a handful of non-HLA risk loci have been identified, capturing the unexplained genetic contribution to AS pathogenesis remains a challenge attributed to additive, pleiotropic and epistatic-interactions at the mo...

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Pubblicato in:Sci Rep
Autori principali: Uddin, Mohammed, Codner, Dianne, Mahmud Hasan, S M, Scherer, Stephen W, O’Rielly, Darren D, Rahman, Proton
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434845/
https://ncbi.nlm.nih.gov/pubmed/25980808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep10314
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