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Pharmacogenetics of rheumatoid arthritis: Potential targets from susceptibility genes and present therapies

Rheumatoid arthritis (RA) is a chronic heterogeneous autoimmune disorder of unknown etiology resulting in inflammation in the synovium, cartilage, and bone. Genetic factors play an important role in susceptibility to RA as the heritability of RA is between 50% and 60%, with the human leukocyte antig...

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Hlavní autoři: O’Rielly, Darren D, Rahman, Proton
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3513198/
https://ncbi.nlm.nih.gov/pubmed/23226040
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