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The Drosophila TIPE family member Sigmar interacts with the Ste20-like kinase Misshapen and modulates JNK signaling, cytoskeletal remodeling and autophagy

TNFAIP8 and other mammalian TIPE family proteins have attracted increased interest due to their associations with disease-related processes including oncogenic transformation, metastasis, and inflammation. The molecular and cellular functions of TIPE family proteins are still not well understood. He...

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Detalhes bibliográficos
Publicado no:Biol Open
Main Authors: Chittaranjan, Suganthi, Xu, Jing, Kuzyk, Michael, Dullat, Harpreet K., Wilton, James, DeVorkin, Lindsay, Lebovitz, Chandra, Morin, Gregg B., Marra, Marco A., Gorski, Sharon M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434819/
https://ncbi.nlm.nih.gov/pubmed/25836674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.20148417
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