IL-33 activates tumor stroma to promote intestinal polyposis

Tumor epithelial cells develop within a microenvironment consisting of extracellular matrix, growth factors, and cytokines produced by nonepithelial stromal cells. In response to paracrine signals from tumor epithelia, stromal cells modify the microenvironment to promote tumor growth and metastasis....

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Maywald, Rebecca L., Doerner, Stephanie K., Pastorelli, Luca, De Salvo, Carlo, Benton, Susan M., Dawson, Emily P., Lanza, Denise G., Berger, Nathan A., Markowitz, Sanford D., Lenz, Heinz-Josef, Nadeau, Joseph H., Pizarro, Theresa T., Heaney, Jason D.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2015
Témata:
PNAS Plus
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434739/
https://ncbi.nlm.nih.gov/pubmed/25918379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422445112
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