Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons

Central glutamatergic synapses and the molecular pathways that control them are emerging as common substrates in the pathogenesis of mental disorders. Genetic variation in the contactin associated protein-like 2 (CNTNAP2) gene, including copy number variations, exon deletions, truncations, single nu...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Varea, Olga, Martin-de-Saavedra, Maria Dolores, Kopeikina, Katherine J., Schürmann, Britta, Fleming, Hunter J., Fawcett-Patel, Jessica M., Bach, Anthony, Jang, Seil, Peles, Elior, Kim, Eunjoon, Penzes, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434727/
https://ncbi.nlm.nih.gov/pubmed/25918374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423205112
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