Synaptic abnormalities and cytoplasmic glutamate receptor aggregates in contactin associated protein-like 2/Caspr2 knockout neurons

Central glutamatergic synapses and the molecular pathways that control them are emerging as common substrates in the pathogenesis of mental disorders. Genetic variation in the contactin associated protein-like 2 (CNTNAP2) gene, including copy number variations, exon deletions, truncations, single nu...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphovsmän: Varea, Olga, Martin-de-Saavedra, Maria Dolores, Kopeikina, Katherine J., Schürmann, Britta, Fleming, Hunter J., Fawcett-Patel, Jessica M., Bach, Anthony, Jang, Seil, Peles, Elior, Kim, Eunjoon, Penzes, Peter
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2015
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4434727/
https://ncbi.nlm.nih.gov/pubmed/25918374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423205112
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