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Altered epitope expression of human interstitial fluid apolipoprotein A-I reduces its ability to activate lecithin cholesterol acyl transferase.

In human peripheral interstitial fluid, esterification of cholesterol by lecithin cholesterol acyltransferase (LCAT) was found to occur at a rate of only 10% of that in plasma (5.6 +/- 1.8 compared with 55.6 +/- 7.8 nmol/ml per h). Measurement of cholesterol esterification in the presence of excess...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Principais autores: Wong, L, Curtiss, L K, Huang, J, Mann, C J, Maldonado, B, Roheim, P S
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443392/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281832/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116127
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