Arginine 123 of apolipoprotein A-I is essential for lecithin:cholesterol acyltransferase activity
ApoA-I activates LCAT that converts lipoprotein cholesterol to cholesteryl ester (CE). Molecular dynamic simulations suggested earlier that helices 5 of two antiparallel apoA-I molecules on discoidal HDL form an amphipathic tunnel for migration of acyl chains and unesterified cholesterol to the acti...
Kaydedildi:
| Asıl Yazarlar: | , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Elsevier
2018-02-01
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| Seri Bilgileri: | Journal of Lipid Research |
| Konular: | |
| Online Erişim: | http://www.sciencedirect.com/science/article/pii/S0022227520342371 |
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