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Mechanistic Assessment of PD-1H Coinhibitory Receptor-Induced T-Cell Tolerance to Allogeneic Antigens()

PD-1H is a recently identified cell surface co-inhibitory molecule of the B7/CD28 immune modulatory gene family. We showed previously that single injection of a PD-1H agonistic monoclonal antibody (mAb) protected mice from graft versus host disease (GVHD). We report here two distinct mechanisms oper...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Flies, Dallas B., Higuchi, Tomoe, Chen, Lieping
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433880/
https://ncbi.nlm.nih.gov/pubmed/25917101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402648
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