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Coinhibitory receptor PD-1H preferentially suppresses CD4(+) T cell–mediated immunity
T cell activation is regulated by the interactions of surface receptors with stimulatory and inhibitory ligands. Programmed death-1 homolog (PD-1H, also called VISTA) is a member of the CD28 family of proteins and has been shown to act as a coinhibitory ligand on APCs that suppress T cell responses....
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Clinical Investigation
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4001557/ https://ncbi.nlm.nih.gov/pubmed/24743150 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI74589 |
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