Hypoxia-mediated induction of endothelial cell interleukin-1 alpha. An autocrine mechanism promoting expression of leukocyte adhesion molecules on the vessel surface.

Tissue injury that accompanies hypoxemia/reoxygenation shares features with the host response in inflammation, suggesting that cytokines, such as IL-1, may act as mediators in this setting. Human endothelial cells (ECs) subjected to hypoxia (PO2 approximately 12-14 Torr) elaborated IL-1 activity int...

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Main Authors: Shreeniwas, R, Koga, S, Karakurum, M, Pinsky, D, Kaiser, E, Brett, J, Wolitzky, B A, Norton, C, Plocinski, J, Benjamin, W
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC443387/
https://ncbi.nlm.nih.gov/pubmed/1281830
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