Lipopolysaccharide binding protein enhances the responsiveness of alveolar macrophages to bacterial lipopolysaccharide. Implications for cytokine production in normal and injured lungs.

A plasma lipopolysaccharide (LPS)-binding protein (LBP) has been shown to regulate the response of rabbit peritoneal macrophages and human blood monocytes to endotoxin (LPS). We investigated whether LBP is present in lung fluids and the effects of LBP on the response of lung macrophages to LPS. Immu...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Martin, T R, Mathison, J C, Tobias, P S, Letúrcq, D J, Moriarty, A M, Maunder, R J, Ulevitch, R J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443371/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1281827/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116106
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