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Participation of tumor necrosis factor in the mediation of gram negative bacterial lipopolysaccharide-induced injury in rabbits.

Macrophages are induced by LPS to release a number of products that determine the host response during gram negative sepsis. To examine the role of one such substance, tumor necrosis factor (TNF), in mediating LPS-induced injury, we employed a rabbit model of endotoxic shock to (a) determine the kin...

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Bibliographic Details
Main Authors: Mathison, J C, Wolfson, E, Ulevitch, R J
Format: Artigo
Language:Inglês
Published: 1988
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC442645/
https://ncbi.nlm.nih.gov/pubmed/3384955
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