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Human Phospholipase D Activity Transiently Regulates Pyrimidine Biosynthesis in Malignant Gliomas
[Image: see text] Cancer cells reorganize their metabolic pathways to fuel demanding rates of proliferation. Oftentimes, these metabolic phenotypes lie downstream of prominent oncogenes. The lipid signaling molecule phosphatidic acid (PtdOH), which is produced by the hydrolytic enzyme phospholipase...
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| Pubblicato in: | ACS Chem Biol |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433586/ https://ncbi.nlm.nih.gov/pubmed/25646564 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb500772c |
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