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Highly PEGylated DNA Nanoparticles Provide Uniform and Widespread Gene Transfer in the Brain
Gene delivery to the central nervous system (CNS) has potential as a means for treating numerous debilitating neurological diseases. Non-viral gene vector platforms are tailorable and can overcome key limitations intrinsic to virus-mediated delivery; however, lack of clinical efficacy with non-viral...
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| Publicado en: | Adv Healthc Mater |
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| Autores principales: | , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433405/ https://ncbi.nlm.nih.gov/pubmed/25761435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201400800 |
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