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Calorie restriction delays spontaneous tumorigenesis in p53-knockout transgenic mice.

Transgenic mice with both alleles of the p53 tumor suppressor gene (frequently mutated in human tumors) knocked out by gene targeting provide a potentially useful tumorigenesis model because these mice rapidly develop spontaneous tumors. To determine whether tumorigenesis in p53-knockout mice is sen...

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Bibliografski detalji
Glavni autori: Hursting, S D, Perkins, S N, Phang, J M
Format: Artigo
Jezik:Inglês
Izdano: 1994
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC44333/
https://ncbi.nlm.nih.gov/pubmed/8041741
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