Enhancement of macrophage candidacidal activity by interferon-gamma. Increased phagocytosis, killing, and calcium signal mediated by a decreased number of mannose receptors.

In contrast to its macrophage-activating capacity, IFN-gamma downregulates expression of the macrophage mannose receptor (MMR), which mediates uptake of Candida and other microorganisms. We found that IFN-gamma induced a concentration-dependent increase in the capacity of human monocyte-derived macr...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Maródi, L, Schreiber, S, Anderson, D C, MacDermott, R P, Korchak, H M, Johnston, R B
Format: Artigo
Jezik:Inglês
Izdano: 1993
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC443323/
https://ncbi.nlm.nih.gov/pubmed/8390485
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki