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Loss of Serglycin Promotes Primary Tumor Growth and Vessel Functionality in the RIP1-Tag2 Mouse Model for Spontaneous Insulinoma Formation

The serglycin proteoglycan is mainly expressed by hematopoietic cells where the major function is to retain the content of storage granules and vesicles. In recent years, expression of serglycin has also been found in different forms of human malignancies and a high serglycin expression level has be...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Hamilton, Andrew, Basic, Vladimir, Andersson, Sandra, Abrink, Magnus, Ringvall, Maria
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433182/
https://ncbi.nlm.nih.gov/pubmed/25978773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0126688
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