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Distal Spike Initiation Zone Location Estimation by Morphological Simulation of Ionic Current Filtering Demonstrated in a Novel Model of an Identified Drosophila Motoneuron

Studying ion channel currents generated distally from the recording site is difficult because of artifacts caused by poor space clamp and membrane filtering. A computational model can quantify artifact parameters for correction by simulating the currents only if their exact anatomical location is kn...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Günay, Cengiz, Sieling, Fred H., Dharmar, Logesh, Lin, Wei-Hsiang, Wolfram, Verena, Marley, Richard, Baines, Richard A., Prinz, Astrid A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433181/
https://ncbi.nlm.nih.gov/pubmed/25978332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004189
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