Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine

BACKGROUND: Ossabaw miniature swine when fed a diet high in fructose, saturated fat and cholesterol (NASH diet) develop metabolic syndrome and nonalcoholic steatohepatitis (NASH) characterized by liver injury and fibrosis. This study was conducted to further characterize the development of NASH in t...

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Udgivet i:PLoS One
Main Authors: Liang, Tiebing, Alloosh, Mouhamad, Bell, Lauren N., Fullenkamp, Allison, Saxena, Romil, Van Alstine, William, Bybee, Phelan, Werling, Klára, Sturek, Michael, Chalasani, Naga, Masuoka, Howard C.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433111/
https://ncbi.nlm.nih.gov/pubmed/25978364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124173
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