Liver Injury and Fibrosis Induced by Dietary Challenge in the Ossabaw Miniature Swine

BACKGROUND: Ossabaw miniature swine when fed a diet high in fructose, saturated fat and cholesterol (NASH diet) develop metabolic syndrome and nonalcoholic steatohepatitis (NASH) characterized by liver injury and fibrosis. This study was conducted to further characterize the development of NASH in t...

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Gepubliceerd in:PLoS One
Hoofdauteurs: Liang, Tiebing, Alloosh, Mouhamad, Bell, Lauren N., Fullenkamp, Allison, Saxena, Romil, Van Alstine, William, Bybee, Phelan, Werling, Klára, Sturek, Michael, Chalasani, Naga, Masuoka, Howard C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433111/
https://ncbi.nlm.nih.gov/pubmed/25978364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124173
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