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Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation
BACKGROUND: Adjusting the capacity of metabolic pathways in response to rapidly changing environmental conditions is an important component of microbial adaptation strategies to stochastic environments. In this work, we use advanced dynamic optimization techniques combined with theoretical models to...
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| Veröffentlicht in: | BMC Bioinformatics |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BioMed Central
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4433072/ https://ncbi.nlm.nih.gov/pubmed/25982966 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0587-z |
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