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Optimal programs of pathway control: dissecting the influence of pathway topology and feedback inhibition on pathway regulation

BACKGROUND: Adjusting the capacity of metabolic pathways in response to rapidly changing environmental conditions is an important component of microbial adaptation strategies to stochastic environments. In this work, we use advanced dynamic optimization techniques combined with theoretical models to...

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Detalhes bibliográficos
Publicado no:BMC Bioinformatics
Main Authors: de Hijas-Liste, Gundián M, Balsa-Canto, Eva, Ewald, Jan, Bartl, Martin, Li, Pu, Banga, Julio R, Kaleta, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433072/
https://ncbi.nlm.nih.gov/pubmed/25982966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0587-z
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