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Applications of CRISPR-Cas9 mediated genome engineering

Targeted mutagenesis based on homologous recombination has been a powerful tool for understanding the mechanisms underlying development, normal physiology, and disease. A recent breakthrough in genome engineering technology based on the class of RNA-guided endonucleases, such as clustered regularly...

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Dades bibliogràfiques
Publicat a:Mil Med Res
Autor principal: Yang, Xiao
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4433013/
https://ncbi.nlm.nih.gov/pubmed/25984354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40779-015-0038-1
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