Apolipoprotein E-dependent load of white matter hyperintensities in Alzheimer’s disease: a voxel-based lesion mapping study

INTRODUCTION: White matter (WM) magnetic resonance imaging (MRI) hyperintensities are common in Alzheimer’s disease (AD), but their pathophysiological relevance and relationship to genetic factors are unclear. In the present study, we investigated potential apolipoprotein E (APOE)-dependent effects...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Morgen, Katrin, Schneider, Michael, Frölich, Lutz, Tost, Heike, Plichta, Michael M, Kölsch, Heike, Rakebrandt, Fabian, Rienhoff, Otto, Jessen, Frank, Peters, Oliver, Jahn, Holger, Luckhaus, Christian, Hüll, Michael, Gertz, Hermann-Josef, Schröder, Johannes, Hampel, Harald, Teipel, Stefan J, Pantel, Johannes, Heuser, Isabella, Wiltfang, Jens, Rüther, Eckart, Kornhuber, Johannes, Maier, Wolfgang, Meyer-Lindenberg, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432954/
https://ncbi.nlm.nih.gov/pubmed/25984242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-015-0111-8
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