Incremental value of biomarker combinations to predict progression of mild cognitive impairment to Alzheimer’s dementia

Abstract Background The progression of mild cognitive impairment (MCI) to Alzheimer’s disease (AD) dementia can be predicted by cognitive, neuroimaging, and cerebrospinal fluid (CSF) markers. Since most biomarkers reveal complementary information, a combination of biomarkers may increase the predict...

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Detalhes bibliográficos
Main Authors: Lutz Frölich, Oliver Peters, Piotr Lewczuk, Oliver Gruber, Stefan J. Teipel, Hermann J. Gertz, Holger Jahn, Frank Jessen, Alexander Kurz, Christian Luckhaus, Michael Hüll, Johannes Pantel, Friedel M. Reischies, Johannes Schröder, Michael Wagner, Otto Rienhoff, Stefanie Wolf, Chris Bauer, Johannes Schuchhardt, Isabella Heuser, Eckart Rüther, Fritz Henn, Wolfgang Maier, Jens Wiltfang, Johannes Kornhuber
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2017-10-01
Colecção:Alzheimer’s Research & Therapy
Assuntos:
Mild cognitive impairment
Biomarkers
Tau
Phospho-tau
Amyloid-beta 42
Hippocampal volume
Acesso em linha:http://link.springer.com/article/10.1186/s13195-017-0301-7
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