CGGBP1 mitigates cytosine methylation at repetitive DNA sequences

BACKGROUND: CGGBP1 is a repetitive DNA-binding transcription regulator with target sites at CpG-rich sequences such as CGG repeats and Alu-SINEs and L1-LINEs. The role of CGGBP1 as a possible mediator of CpG methylation however remains unknown. At CpG-rich sequences cytosine methylation is a major m...

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Pubblicato in:BMC Genomics
Autori principali: Agarwal, Prasoon, Collier, Paul, Fritz, Markus Hsi-Yang, Benes, Vladimir, Wiklund, Helena Jernberg, Westermark, Bengt, Singh, Umashankar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2015
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432828/
https://ncbi.nlm.nih.gov/pubmed/25981527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1593-2
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