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Lenalidomide reduces microglial activation and behavioral deficits in a transgenic model of Parkinson’s disease

BACKGROUND: Parkinson’s disease (PD) is one of the most common causes of dementia and motor deficits in the elderly. PD is characterized by the abnormal accumulation of the synaptic protein alpha-synuclein (α-syn) and degeneration of dopaminergic neurons in substantia nigra, which leads to neurodege...

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Detalhes bibliográficos
Publicado no:J Neuroinflammation
Main Authors: Valera, Elvira, Mante, Michael, Anderson, Scott, Rockenstein, Edward, Masliah, Eliezer
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432827/
https://ncbi.nlm.nih.gov/pubmed/25966683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12974-015-0320-x
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