Two distinct mechanisms for bilirubin glucuronide transport by rat bile canalicular membrane vesicles. Demonstration of defective ATP-dependent transport in rats (TR-) with inherited conjugated hyperbilirubinemia.

Bilirubin is conjugated with glucuronic acid in hepatocytes and subsequently secreted in bile. The major conjugate is bilirubin diglucuronide. Using sealed vesicles which are primarily derived from the canalicular (CMV) and sinusoidal (SMV) membrane vesicle domains of the plasma membrane of hepatocy...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Nishida, T, Gatmaitan, Z, Roy-Chowdhry, J, Arias, I M
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1992
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC443282/
https://ncbi.nlm.nih.gov/pubmed/1430236
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi