Inhibition of Outer Membrane Proteases of the Omptin Family by Aprotinin

Bacterial proteases are important virulence factors that inactivate host defense proteins and contribute to tissue destruction and bacterial dissemination. Outer membrane proteases of the omptin family, exemplified by Escherichia coli OmpT, are found in some Gram-negative bacteria. Omptins cleave a...

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Bibliografiska uppgifter
I publikationen:Infect Immun
Huvudupphovsmän: Brannon, John R., Burk, David L., Leclerc, Jean-Mathieu, Thomassin, Jenny-Lee, Portt, Andrea, Berghuis, Albert M., Gruenheid, Samantha, Le Moual, Hervé
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2015
Ämnen:
Molecular Pathogenesis
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432765/
https://ncbi.nlm.nih.gov/pubmed/25824836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00136-15
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