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Inhibition of Outer Membrane Proteases of the Omptin Family by Aprotinin

Bacterial proteases are important virulence factors that inactivate host defense proteins and contribute to tissue destruction and bacterial dissemination. Outer membrane proteases of the omptin family, exemplified by Escherichia coli OmpT, are found in some Gram-negative bacteria. Omptins cleave a...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Brannon, John R., Burk, David L., Leclerc, Jean-Mathieu, Thomassin, Jenny-Lee, Portt, Andrea, Berghuis, Albert M., Gruenheid, Samantha, Le Moual, Hervé
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432765/
https://ncbi.nlm.nih.gov/pubmed/25824836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00136-15
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