Inhibition of Outer Membrane Proteases of the Omptin Family by Aprotinin

Bacterial proteases are important virulence factors that inactivate host defense proteins and contribute to tissue destruction and bacterial dissemination. Outer membrane proteases of the omptin family, exemplified by Escherichia coli OmpT, are found in some Gram-negative bacteria. Omptins cleave a...

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Udgivet i:Infect Immun
Main Authors: Brannon, John R., Burk, David L., Leclerc, Jean-Mathieu, Thomassin, Jenny-Lee, Portt, Andrea, Berghuis, Albert M., Gruenheid, Samantha, Le Moual, Hervé
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Molecular Pathogenesis
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432765/
https://ncbi.nlm.nih.gov/pubmed/25824836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00136-15
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