Intrauterine Infection with Plasmid-Free Chlamydia muridarum Reveals a Critical Role of the Plasmid in Chlamydial Ascension and Establishes a Model for Evaluating Plasmid-Independent Pathogenicity

Intravaginal infection with plasmid-competent but not plasmid-free Chlamydia muridarum induces hydrosalpinx in mouse upper genital tract, indicating a critical role of the plasmid in chlamydial pathogenicity. To evaluate the contribution of the plasmid to chlamydial ascension and activation of tubal...

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Publicado en:Infect Immun
Autores principales: Chen, Jianlin, Yang, Zhangsheng, Sun, Xin, Tang, Lingli, Ding, Yiling, Xue, Min, Zhou, Zhiguang, Baseman, Joel, Zhong, Guangming
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Bacterial Infections
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432736/
https://ncbi.nlm.nih.gov/pubmed/25870225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00353-15
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