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Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance.

Insulin rapidly stimulates tyrosine phosphorylation of a protein of approximately 185 kD in most cell types. This protein, termed insulin receptor substrate-1 (IRS-1), has been implicated in insulin signal transmission based on studies with insulin receptor mutants. In the present study we have exam...

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Bibliographic Details
Main Authors: Saad, M J, Araki, E, Miralpeix, M, Rothenberg, P L, White, M F, Kahn, C R
Format: Artigo
Language:Inglês
Published: 1992
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC443244/
https://ncbi.nlm.nih.gov/pubmed/1331176
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