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Subtype-dependent N-Methyl-d-aspartate Receptor Amino-terminal Domain Conformations and Modulation by Spermine

The N-methyl-d-aspartate (NMDA) subtype of the ionotropic glutamate receptors is the primary mediator of calcium-permeable excitatory neurotransmission in the central nervous system. Subunit composition and binding of allosteric modulators to the amino-terminal domain determine the open probability...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Sirrieh, Rita E., MacLean, David M., Jayaraman, Vasanthi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432297/
https://ncbi.nlm.nih.gov/pubmed/25829490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.649723
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