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EDD, a Ubiquitin-protein Ligase of the N-end Rule Pathway, Associates with Spindle Assembly Checkpoint Components and Regulates the Mitotic Response to Nocodazole

In this work, we identify physical and genetic interactions that implicate E3 identified by differential display (EDD) in promoting spindle assembly checkpoint (SAC) function. During mitosis, the SAC initiates a mitotic checkpoint in response to chromosomes with kinetochores unattached to spindle po...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Scialpi, Flavia, Mellis, David, Ditzel, Mark
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432279/
https://ncbi.nlm.nih.gov/pubmed/25833949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.625673
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