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UreE-UreG Complex Facilitates Nickel Transfer and Preactivates GTPase of UreG in Helicobacter pylori

The pathogenicity of Helicobacter pylori relies heavily on urease, which converts urea to ammonia to neutralize the stomach acid. Incorporation of Ni(2+) into the active site of urease requires a battery of chaperones. Both metallochaperones UreE and UreG play important roles in the urease activatio...

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Publicado en:J Biol Chem
Autores principales: Yang, Xinming, Li, Hongyan, Lai, Tsz-Pui, Sun, Hongzhe
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432268/
https://ncbi.nlm.nih.gov/pubmed/25752610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.632364
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