In Vivo Antimalarial Activity and Mechanisms of Action of 4-Nerolidylcatechol Derivatives

4-Nerolidylcatechol (1) is an abundant antiplasmodial metabolite that is isolated from Piper peltatum roots. O-Acylation or O-alkylation of compound 1 provides derivatives exhibiting improved stability and significant in vitro antiplasmodial activity. The aim of this work was to study the in vitro i...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Rocha e Silva, Luiz Francisco, Nogueira, Karla Lagos, Pinto, Ana Cristina da Silva, Katzin, Alejandro Miguel, Sussmann, Rodrigo A. C., Muniz, Magno Perêa, Neto, Valter Ferreira de Andrade, Chaves, Francisco Célio Maia, Coutinho, Julia Penna, Lima, Emerson Silva, Krettli, Antoniana Ursine, Tadei, Wanderli Pedro, Pohlit, Adrian Martin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432218/
https://ncbi.nlm.nih.gov/pubmed/25801563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05012-14
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