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N-Acetylcysteine Selectively Antagonizes the Activity of Imipenem in Pseudomonas aeruginosa by an OprD-Mediated Mechanism

The modulating effect of N-acetylcysteine (NAC) on the activity of different antibiotics has been studied in Pseudomonas aeruginosa. Our results demonstrate that, in contrast to previous reports, only the activity of imipenem is clearly affected by NAC. MIC and checkerboard determinations indicate t...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Rodríguez-Beltrán, Jerónimo, Cabot, Gabriel, Valencia, Estela Ynés, Costas, Coloma, Bou, German, Oliver, Antonio, Blázquez, Jesús
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432192/
https://ncbi.nlm.nih.gov/pubmed/25801561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00017-15
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