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Effect of a High-Fat Meal on the Pharmacokinetics of 300-Milligram Posaconazole in a Solid Oral Tablet Formulation
Posaconazole in oral suspension must be taken multiple times a day with food (preferably a high-fat meal) to ensure adequate exposure among patients. We evaluated the effect of food on the bioavailability of a new delayed-release tablet formulation of posaconazole at the proposed clinical dose of 30...
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Udgivet i: | Antimicrob Agents Chemother |
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Main Authors: | , , , , , , |
Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
American Society for Microbiology
2015
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4432131/ https://ncbi.nlm.nih.gov/pubmed/25824210 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05000-14 |
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