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Effect of a High-Fat Meal on the Pharmacokinetics of 300-Milligram Posaconazole in a Solid Oral Tablet Formulation

Posaconazole in oral suspension must be taken multiple times a day with food (preferably a high-fat meal) to ensure adequate exposure among patients. We evaluated the effect of food on the bioavailability of a new delayed-release tablet formulation of posaconazole at the proposed clinical dose of 30...

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Bibliografische gegevens
Gepubliceerd in:Antimicrob Agents Chemother
Hoofdauteurs: Kersemaekers, Wendy M., Dogterom, Peter, Xu, Jialin, Marcantonio, Eugene E., de Greef, Rik, Waskin, Hetty, van Iersel, Marlou L. P. S.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432131/
https://ncbi.nlm.nih.gov/pubmed/25824210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05000-14
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