Pharmacokinetics and Safety Study of Posaconazole Intravenous Solution Administered Peripherally to Healthy Subjects

This study evaluated the safety, tolerability, and pharmacokinetics of a posaconazole i.v. (intravenous) solution. This was a single-center, 2-part, randomized, rising single- and multiple-dose study in healthy adults. In part 1, subjects received 0 (vehicle), 50, 100, 200, 250, or 300 mg posaconazo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Principais autores: Kersemaekers, Wendy M., van Iersel, Thijs, Nassander, Ulla, O'Mara, Edward, Waskin, Hetty, Caceres, Maria, van Iersel, Marlou L. P. S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Clinical Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4335848/
https://ncbi.nlm.nih.gov/pubmed/25512407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04223-14
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