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Granulocyte colony-stimulating factor reprograms bone marrow stromal cells to actively suppress B lymphopoiesis in mice

The mechanisms that mediate the shift from lymphopoiesis to myelopoiesis in response to infectious stress are largely unknown. We show that treatment with granulocyte colony-stimulating factor (G-CSF), which is often induced during infection, results in marked suppression of B lymphopoiesis at multi...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Day, Ryan B., Bhattacharya, Deepta, Nagasawa, Takashi, Link, Daniel C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4432005/
https://ncbi.nlm.nih.gov/pubmed/25814527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2015-02-629444
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