Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure.

The intrarenal renin-angiotensin system (RAS) may contribute to the pathophysiology of heart failure by the generation of angiotensin II at local sites within the kidneys. Angiotensin II may directly influence renal hemodynamics, glomerular contractility, and tubular sodium reabsorption, thereby pro...

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Bibliografiske detaljer

Udgivet i:	J Clin Invest
Principais autores:	Schunkert, H, Ingelfinger, J R, Hirsch, A T, Tang, S S, Litwin, S E, Talsness, C E, Dzau, V J
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Clinical Investigation 1992
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116020
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