Evidence for tissue-specific activation of renal angiotensinogen mRNA expression in chronic stable experimental heart failure.

The intrarenal renin-angiotensin system (RAS) may contribute to the pathophysiology of heart failure by the generation of angiotensin II at local sites within the kidneys. Angiotensin II may directly influence renal hemodynamics, glomerular contractility, and tubular sodium reabsorption, thereby pro...

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Detalhes bibliográficos

Publicado no:	J Clin Invest
Principais autores:	Schunkert, H, Ingelfinger, J R, Hirsch, A T, Tang, S S, Litwin, S E, Talsness, C E, Dzau, V J
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Clinical Investigation 1992
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443199/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401084/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116020
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