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Characterization of the cDNA of a broadly reactive neutralizing human anti-gp120 monoclonal antibody.
The F105 mAb, identified in an HIV-1-infected individual, binds to a discontinuous epitope on the HIV-1 gp120 envelope glycoprotein, blocks the binding of gp120 to the CD4 viral receptor, and neutralizes a broad range of HIV-1 isolates. This study reports the primary nucleotide and deduced amino aci...
Enregistré dans:
| Publié dans: | J Clin Invest |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
1992
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443193/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401079/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI116014 |
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