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Copper intoxication inhibits aerobic nucleotide synthesis in Streptococcus pneumoniae

Copper is universally toxic in excess, a feature exploited by the human immune system to facilitate bacterial clearance. The mechanism of copper intoxication remains unknown for many bacterial species. Here, we demonstrate that copper toxicity in Streptococcus pneumoniae is independent from oxidativ...

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Detalhes bibliográficos
Publicado no:Metallomics
Main Authors: Johnson, Michael D. L., Kehl-Fie, Thomas E., Rosch, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431907/
https://ncbi.nlm.nih.gov/pubmed/25730343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5mt00011d
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