Role of Copper Efflux in Pneumococcal Pathogenesis and Resistance to Macrophage-Mediated Immune Clearance

In bacteria, the intracellular levels of metals are mediated by tightly controlled acquisition and efflux systems. This is particularly true of copper, a trace element that is universally toxic in excess. During infection, the toxic properties of copper are exploited by the mammalian host to facilit...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Johnson, Michael D. L., Kehl-Fie, Thomas E., Klein, Roger, Kelly, Jacqueline, Burnham, Corinna, Mann, Beth, Rosch, Jason W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363445/
https://ncbi.nlm.nih.gov/pubmed/25667262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.03015-14
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