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Myeloid Translocation Gene-16 Co-Repressor Promotes Degradation of Hypoxia-Inducible Factor 1

The myeloid translocation gene 16 (MTG16) co-repressor down regulates expression of multiple glycolytic genes, which are targets of the hypoxia-inducible factor 1 (HIF1) heterodimer transcription factor that is composed of oxygen-regulated labile HIF1α and stable HIF1β subunits. For this reason, we...

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Veröffentlicht in:PLoS One
Hauptverfasser: Kumar, Parveen, Gullberg, Urban, Olsson, Inge, Ajore, Ram
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431712/
https://ncbi.nlm.nih.gov/pubmed/25974097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123725
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