Maturation of aldose reductase expression in the neonatal rat inner medulla.

Newborns are less able to concentrate urine than adults are. With development of the concentrating system and a hypertonic medullary interstitium, there is a need to generate intracellular osmolytes such as sorbitol, which is produced in a reaction catalyzed by the enzyme aldose reductase. We sought...

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Veröffentlicht in:	J Clin Invest
Hauptverfasser:	Schwartz, G J, Zavilowitz, B J, Radice, A D, Garcia-Perez, A, Sands, J M
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical Investigation 1992
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC443170/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1401064/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI115991
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