Reduction of mitochondrial H(2)O(2) by overexpressing peroxiredoxin 3 improves glucose tolerance in mice

H(2)O(2) is a major reactive oxygen species produced by mitochondria that is implicated to be important in aging and pathogenesis of diseases such as diabetes; however, the cellular and physiological roles of mitochondrial H(2)O(2) remain poorly understood. Peroxiredoxin 3 (Prdx3/Prx3) is a thioredo...

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Pubblicato in:Aging Cell
Autori principali: Chen, Liuji, Na, Ren, Gu, Mingjun, Salmon, Adam B., Liu, Yuhong, Liang, Hanyu, Qi, Wenbo, Van Remmen, Holly, Richardson, Arlan, Ran, Qitao
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2008
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431549/
https://ncbi.nlm.nih.gov/pubmed/18778410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2008.00432.x
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