Role of the Tau N-terminal region in microtubule stabilization revealed by new endogenous truncated forms

Tau is a central player in Alzheimer's disease (AD) and related Tauopathies, where it is found as aggregates in degenerating neurons. Abnormal post-translational modifications, such as truncation, are likely involved in the pathological process. A major step forward in understanding the role of...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Derisbourg, Maxime, Leghay, Coline, Chiappetta, Giovanni, Fernandez-Gomez, Francisco-Jose, Laurent, Cyril, Demeyer, Dominique, Carrier, Sébastien, Buée-Scherrer, Valérie, Blum, David, Vinh, Joëlle, Sergeant, Nicolas, Verdier, Yann, Buée, Luc, Hamdane, Malika
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431475/
https://ncbi.nlm.nih.gov/pubmed/25974414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09659
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados