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Efficacy and safety of ascending methotrexate dose in combination with adalimumab: the randomised CONCERTO trial

OBJECTIVE: CONCERTO was a randomised, double-blind, parallel-armed study of methotrexate (MTX) in combination with adalimumab to assess whether an increasing trend of efficacy and decreased safety exists when increasing MTX dose in patients with early rheumatoid arthritis (RA). METHODS: Early, biolo...

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Detalles Bibliográficos
Publicado en:Ann Rheum Dis
Main Authors: Burmester, Gerd-Rűdiger, Kivitz, Alan J, Kupper, Hartmut, Arulmani, Udayasankar, Florentinus, Stefan, Goss, Sandra L, Rathmann, Suchitrita S, Fleischmann, Roy M
Formato: Artigo
Idioma:Inglês
Publicado: BMJ Publishing Group 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4431334/
https://ncbi.nlm.nih.gov/pubmed/24550168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2013-204769
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